Elvitegravir concentrations in seminal plasma in HIV-1-infected men
نویسندگان
چکیده
منابع مشابه
Etravirine concentrations in seminal plasma in HIV-infected patients.
OBJECTIVES To determine etravirine concentrations and the HIV-1 viral load (VL) in blood plasma (BP) and seminal plasma (SP) of HIV-infected patients. METHODS Ten adult antiretroviral-experienced HIV-1 patients receiving an etravirine-containing regimen for at least 1 month were enrolled. Semen and blood samples were collected ~12 or 24 h after the last etravirine dose, depending on twice-dai...
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BACKGROUND Xenotropic murine leukaemia virus-related virus (XMRV) is a recently discovered human gammaretrovirus with yet unknown prevalence and transmission route(s). Its presence in prostate stromal fibroblasts and prostatic secretions suggests that XMRV might be sexually transmitted. We chose to study a compartment closely connected to the prostate, a location where XMRV was detected in inde...
متن کاملAntiretroviral drug concentrations in semen of HIV-1 infected men.
Because semen is a major vehicle for the sexual transmission of HIV-1, control of viral replication within the sanctuary of the male genital tract should be a goal of antiretroviral therapy. Local immune responses, virus specific factors, and the degree of viral and cellular trafficking all appear to be important in controlling viral replication and evolution. However, the most important factor...
متن کاملSemen alterations in HIV-1 infected men.
BACKGROUND Couples in whom the man is infected by human immunodeficiency virus (HIV) increasingly request assisted reproductive technology (ART) to allow safe procreation. Semen quality is critical in such situations. METHODS Semen characteristics were evaluated in 189 HIV-infected men requesting ART. At the time of semen analysis all men were healthy and 177 were receiving anti-retroviral th...
متن کاملthe leptin concentrations in seminal plasma of men and its relationship to semen parameters
background: leptin is a polypeptide hormone secreted by white adipose tissue in proportion to body energy. although the participation of leptin in female reproduction is well established any role in male reproductive function is at best tenuous. objective: the objective of this study was to compare the leptin concentration in human seminal plasma and then the relationships between seminal lepti...
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ژورنال
عنوان ژورنال: HIV Medicine
سال: 2016
ISSN: 1464-2662
DOI: 10.1111/hiv.12417